MIT, guided by open access principles, ends Elsevier negotiations http://ow.ly/jw0g50A53lO
@MIT @mitlibraries @ElsevierConnect
"Small, observational & non-randomized studies will not give us the answers we need. Using untested 💊 without the right evidence could raise false hope & even do more harm than good & cause a shortage of essential 💊 that are needed to treat other diseases"-@DrTedros #COVID19
FDAAA 2007 is a law that requires certain clinical trials to report results. After a long wait, it effectively came into force for all trials due after January 2018. The FDA are not publicly tracking compliance. So @FDAAAtracker does, here: http://fdaaa.trialstracker.net
#PLOSCompBio: Ten simple rules for getting started on Twitter as a scientist https://dx.plos.org/10.1371/journal.pcbi.1007513
We can reduce disparities in care and research by extending Medicaid coverage to include the routine costs of care associated with clinical trials. @kmdillmon explains at http://bit.ly/334FAuy
.@NEJM publishes new guidelines & and limits use of "P values or confidence intervals as bright-line markers for conclusion/ claim." @NEJM https://www.nejm.org/doi/full/10.1056/NEJMe1906559#.XS-7TSPAS32.twitter
A step in the right direction ! @Lester_Domes @ken_rothman @oacarah @TimothyLash @EpiEllie @dr_katon #epitwitter
Meta-Research: A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals https://doi.org/10.7554/eLife.45183
Rein in the four horsemen of irreproducibility
Dorothy Bishop describes how threats to reproducibility, recognized but unaddressed for decades, might finally be brought under control.
As Dr. Ioannidis has pointed out many times, today's clinical research is fatally flawed. We must insist that the research we all rely on is reproducible.
@ACSHorg @ArenaClinical @METRICStanford @ReproFeed
Yes, blockchain can ensure the integrity of clinical trials. MyIRE, Inc. already has a blockchain-powered platform that does just that.
@atulbutte @GeorginaTorbet @LauraKurtzman @UCSF_ICHS @Slabodkin